How Trump’s Online Drugstore May Affect Your Drug Costs

TrumpRx Launches: Will Trump’s Online Drugstore Actually Lower Your Prescription Costs?

Trump-Pfizer Deal Promises Cheaper Drugs—But Experts Are Skeptical

President Trump and top health officials unveiled a bold new initiative this week: a partnership with pharmaceutical giant Pfizer and a forthcoming federal website, TrumpRx.gov, designed to let Americans buy prescription drugs directly from manufacturers at lower prices.

What’s in the Deal?

The agreement includes two major components:

  • Medicaid price alignment: Pfizer will charge U.S. Medicaid programs prices similar to those in European countries.
  • Direct-to-consumer sales portal: TrumpRx.gov will route users to drugmakers’ direct-sale programs, bypassing traditional pharmacies and insurers.

While the announcement was framed as a breakthrough for American patients, health policy experts warn the real-world impact may be limited.

“It’s a really good way to say you’re doing something about drug prices, and not actually do anything to change the underlying profits of the industry.”
— Dr. Stacie Dusetzina, Vanderbilt University

Who Actually Benefits?

Group Potential Benefit? Why or Why Not
Medicaid Patients ❌ Minimal Already pay ≤$8 per prescription; no out-of-pocket savings expected.
Insured Americans ⚠️ Limited Most drugs are covered by insurance; direct purchase may cost more.
Uninsured or Underinsured ✅ Possible May benefit if their needed drug isn’t covered and is offered via direct-sale.
State Medicaid Programs ✅ Yes Could see lower reimbursement costs for select Pfizer drugs.

Drugs Available Through Direct-Sale Programs

Pfizer plans to include medications like:

  • Duavee – for menopausal hot flashes
  • Eucrisa – for eczema and skin inflammation
  • Toviaz – for overactive bladder

Other manufacturers already offer direct sales for high-demand drugs like:

  • Zepbound (Eli Lilly) – weight-loss drug, $500/month
  • Eliquis (Bristol Myers Squibb) – blood thinner
  • Airsupra (AstraZeneca) – asthma inhaler

Infographic: TrumpRx vs. Alternatives

Prescription drug bottles on a pharmacy shelf

Will You Save Money?

Not necessarily. Take Xeljanz, Pfizer’s arthritis drug:

  • Sticker price: >$6,000/month
  • TrumpRx direct price (40% off): ~$3,600/month
  • Insured co-pay: often just $25/month
  • GoodRx cash price: as low as $2,900/month

For most, using insurance remains far cheaper—even with high deductibles.

Expert Advice

[INTERNAL_LINK:prescription-drug-savings] specialists recommend:

  • Ask your doctor for free samples
  • Check GoodRx or Mark Cuban’s Cost Plus Drugs for generics
  • Explore manufacturer patient assistance programs
  • Avoid bypassing insurance unless absolutely necessary

What’s Next?

TrumpRx.gov is expected to launch in 2026. The administration hinted that deals with other drugmakers—including Novo Nordisk, Eli Lilly, and AstraZeneca—could follow.

Sources

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